Filmed in Rome and Bangkok, the film tells the story of Giulio, who has felt like he was born in the wrong body since he was a child. At the age of 27, he decides to undergo surgery, at a prestigious clinic in Thailand. But once he becomes a woman, he suffers an identity crisis that he overcomes with the help of his companion and lifelong friends.
Stefano is caught with a bag of cocaine in his pocket and placed under house arrest. Yet the boy knows full well that he has never used drugs. There is someone who wants to frame him, but there are also drug traffickers on his trail, convinced that Stefano has made a load of white powder disappear.
Franco Califano, fallen and resurrected several times, begins his third life after the years of drugs and prison, of a youth lived to the last breath, appearing at Sanremo just to come in last in the rankings. But his third life as an artist has just begun, and it takes place during the sold-out concerts organized by his unconventional manager who, instead of choosing high-end venues, sets dates in dance halls and trattorias frequented by the people who love him. Around Franco, his lifelong friends, who have common names, far from show business, and who support and encourage him, look after him while the blows of age and a wild life begin to be felt, while his legend, destined to last, continues to grow.
Valerio, a policeman and kickboxing champion, is about to become a father. His partner Valentina, with whom he is deeply in love, is expecting a child and the young couple's life seems to be going well. Valentina, however, cultivates the desire to become an actress and often finds herself meeting shady individuals such as the film producer and crime boss Sergio Bruschi. Valentina's sudden death following the unknowing intake of the so-called date rape drug during a meeting with Bruschi pushes Valerio to devote himself to an insane and terrible revenge.
Distressed by the uncertainties of a precarious job, Carlo falls prey to an ambiguous financier who, taking advantage of his naivety, offers him unexpected financial help. Carlo accepts, but it doesn't take him long to realize that he has fallen into the trap of an unscrupulous loan shark. It is useless to flee and try to disappear: the heavy threats and humiliations inflicted on his family will force him to commit an extreme act.
Stefano, a solitary killer with a dark past, works as a bouncer in a nightclub to cover up his real occupation. He avoids hanging out with friends and relatives and his only human contact is with young Filippo, who is enrolled in the same gym where he trains. His passion for Chinese food and the Orient leads him to meet Lee Ang, a girl who works in the family restaurant and who, a victim of her father's overbearing severity, begins to secretly date him until he falls in love with her and questions his life and future.
Two different criminal gangs are fighting each other. Not even the police seem to be able to stop the conflict in a Christmas Rome surrounded by drug dealing, corruption, violence and arrogance.
