New York, 1979. U bolnici na Manhattanu Christine se upravo rodila, prekrasna djevojčica. Istog dana u Vatikanu mladi svećenik obavještava Papu o rođenju djeteta koje nosi oznaku Antikrista. Jericho Cane, gorki bivši policajac, 1999. godine spasio je mladu djevojku da je lopovi opljačkali: to je Christine. Od tada će Cane biti žrtva progona strašnih natprirodnih sila.
Christian lives in a "city-palace" where he earns his living doing dirty work for LINO, the criminal boss of neighborhood. When stigmata appear on his hands, Christian finds physically impossible to carry out his work, but also discovers he has gained mysterious healing powers to fight against Lino. But MATTEO, a mysterious Vatican postulator in search of signs and confirmations, is tracking him down bringing too close to a truth that could upset his life and that of the whole world.
