Yakuza-bossen Anjo bliver myrdet og hans sadomasochistiske, bindegale højre hånd Kakihara sætter sig for at finde morderen ved at torturere enhver mistænkt. Samtidig melder den mystiske og brutale lejemorder Ichi sig på banen. Da Kakihara hører om hans evner, så må han bare møde denne smertens mester. Imens forstætter jagten på Anjo morder.
Shinjuku Ward, east side… The center of the street with the most chaos, there's Kabuki-chō, full of neon lights. When the light is stronger, the shadow is deeper. The story begins when certain bizarre murder happens one night! Suspense? Or Comedy? Drama that cannot be identified begins!
A gripping medical drama centered around a hospital in Kabukicho. Featuring a diverse cast of characters, including those from male host bars and street kids many with complicated backgrounds.
Following her father’s disappearance, a principled corporate attorney takes over his practice located in Tokyo’s seedy red-light district of Kabukicho.
