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Taking place mainly in Bogotá, Colombia, Betty La Fea is essentially a Cinderella comedy about the rise of poor, ugly 'Betty' Pinzón and the fall of rich, handsome Armando Mendoza. Armando is a very incompetent playboy with a scheme to turn a huge profit as the new President of Eco Moda, a famous clothing manufacturing company, but his scheme is doomed because of his faulty mathematics. Because Betty, his secretary (and economics wizard), is in love with him, she helps Armando deceive the Board of Directors as he loses money and brings the company to ruin. Betty, la Fea is arguably the most successful telenovela of all time and one of the most popular television shows in the world. It is the first telenovela to have been remade worldwide and has been regarded as bringing the telenovela to new levels of success.

Rafael Méndez and Alejandra Maldonado are salesmen from opposite sides of life. While Méndez depends on informal sales, and that without any higher education degree, Alejandra carries her duties as the Commercial Manager of a car dealership with an MBA degree and a hard attitude up her sleeve. An unfortunate car accident will bring them together, and they will have to get the best of each other in order to survive their respective realities.

Daisy O'Brian is a normal girl who dreams of a singing career in musical comedy. Her parents are vampires, and per her family tradition, she must decide to become a vampire or not on her 16th birthday. On that day, Daisy decides to stay human to live next to her love, Max, who is her neighbor and classmate. However, that same day, a fatal accident changes her life forever. The doctor says to her parents that she is not going to make it. So, her parents decide to bite Daisy, to save her, turning her into a vampire. This makes Vicente (her younger brother) the only mortal in the family. From that moment, Daisy leads a double life full of risks, where she must attend a human school, hiding her nature, and also go to vampire school and take classes for newly bitten vampires.

Emiliano, a wealthy Mexican businessman, is ripped off by his friends and partners. Hidden in Bogotá, he receives help from Rosario, a mariachi singer. She does not know Emiliano’s background and that he is wanted by the police of two countries and by a criminal organization. With a new name and personality, he adapts well to his new life as a mariachi band member and finds in Rosario the love of his life. But he is afraid his secret will tear them apart. He needs to clear his name and resolve his case to avoid that fate. Meanwhile, he often finds his love tested and vulnerable to several rivals, but Rosario always trusts that he has been honest with her.

El Capo, the most wanted drug dealer in Mexico, has been intercepted while hiding with his trusted men, his wife and his lover. During his escape, he declares war on the government and his own past.

Novelized story of Policarpa Salavarrieta, heroine of Colombia's independence movement.

The life story of Colombian film star Lady Tabares, who was plucked off the mean streets to star in a film and quickly rose to fame.

Chepe Fortuna and Niña Cabrales are from different social classes. Chepe is a poor fisherman and Niña is from a wealthy family. He wants to become mayor to stop her wealthy family from building a port to industrialize the town. Niña is an ecologist and dissident from her family. She wants to help the community. Their love is brought together by dreams and the past, though they do not know it.

Rafael Méndez is an ethical and noble man who dedicates his life to selling household items and is dating his neighbor Vicky Pardo. Alejandra Maldonado is a successful businesswoman and manager of the Ramenautos car dealership, she is engaged to Luciano Valenzuela. Rafael and Alejandra suffer a car accident that will trigger a series of events that will bring them closer. Rafael must pay off the debt he has left Alejandra with after the accident and this closeness will lead them to fall in love despite their social differences. However, circumstances and their respective families and partners will do everything possible to prevent their love from happening.

Ana, a dedicated wife and mother, must reinvent her life after divorcing her philandering husband. When she meets and falls in love with a much younger man named Joaquín, her family and future change forever.